Description

Anti-AXL (phosphorylated Y698, Y702 | 708-PTM-CBPAB-0435

Host Animal Rabbit

Specificity Human, Mouse, Rat

Antibody Isotype IgG

Application WB, IHC-P, ELISA

Immunogen KLH conjugated synthetic phosphopeptide derived from human AXL around the phosphorylation site of

Tyr698+Tyr702+Tyr703.

Specificity Human, Mouse, Rat

Antibody IsotypeIgG

Clonality Monoclonal

Application Notes The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

AXL is a member of the Tyro3-Axl-Mer (TAM) receptor tyrosine kinase subfamily. The encoded protein possesses an extracellular domain which is composed of two immunoglobulin-like motifs at the N-terminal, followed by two fibronectin type-III motifs.

It transduces signals from the extracellular matrix into the cytoplasm by binding to the vitamin K-dependent protein growth arrest-specific 6 (Gas6). This gene may be involved in several cellular functions including growth, migration, aggregation and anti-inflammation in multiple cell types.

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